Search on: INTEGRIN ALPHA6BETA1 
Descriptors Found: 1
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Descriptor English:   Integrin alpha6beta1 
Descriptor Spanish:   Integrina alfa6beta1 
Descriptor Portuguese:   Integrina alfa6beta1 
Synonyms English:   CD49f-CD29
Integrin alpha(6)beta(1)
Integrin alpha6Abeta1
Integrin alpha6Bbeta1
Platelet Glycoprotein I'c-IIa
VLA-6
alpha 6 beta 1 Integrin
alpha6beta1 Integrin
CD49f CD29
Glycoprotein I'c-IIa, Platelet
I'c-IIa, Platelet Glycoprotein
Integrin, alpha6beta1
Platelet Glycoprotein I'c IIa
VLA 6
alpha6Abeta1, Integrin
alpha6Bbeta1, Integrin
alpha6beta1, Integrin  
Tree Number:   D12.776.395.550.625.419
D12.776.543.550.625.419
D12.776.543.750.705.408.850.674
D12.776.543.750.705.675.514
D12.776.543.750.705.876.500
Definition English:   A cell surface receptor mediating cell adhesion to the EXTRACELLULAR MATRIX and to other cells via binding to LAMININ. It is involved in cell migration, embryonic development, leukocyte activation and tumor cell invasiveness. Integrin alpha6beta1 is the major laminin receptor on PLATELETS; LEUKOCYTES; and many EPITHELIAL CELLS, and ligand binding may activate a number of signal transduction pathways. Alternative splicing of the cytoplasmic domain of the alpha6 subunit (INTEGRIN ALPHA6) results in the formation of A and B isoforms of the heterodimer, which are expressed in a tissue-specific manner. 
History Note English:   2003; use INTEGRIN ALPHA6BETA1 (NM) 1992-2002 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   37451 
Unique Identifier:   D039121 

Occurrence in VHL:
 

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